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glutamic acid
CAS No. 56-86-0
glutamic acid( Glutamic Acid | Glutamicol | AI3-18472 )
Catalog No. M18825 CAS No. 56-86-0
(S)-Glutamic acid acts as an excitatory transmitter, shows a direct activating effect on the release of DA from dopaminergic terminals.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 25MG | 49 | In Stock |
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| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product Nameglutamic acid
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NoteResearch use only, not for human use.
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Brief Description(S)-Glutamic acid acts as an excitatory transmitter, shows a direct activating effect on the release of DA from dopaminergic terminals.
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DescriptionGlutamic Acid is a non-essential amino acid naturally occurring in the L-form. Glutamic acid is the most common excitatory neurotransmitter in the CENTRAL NERVOUS SYSTEM.
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In VitroCell Viability Assay Cell Line:SH-SY5Y, IMR-32, SK-N-BE(2)Concentration:2, 5, 10, 20 mM Incubation Time:24 and 48 h Result:Reduced cell viability in a dose-dependent manner.
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In VivoAnimal Model:Crv4 mice model Dosage:3 g/kg Administration:s.c., single dose Result:Reduced the number of Brn-3a+ RGCs by >70%.In the absence of mGlu1 receptor, MSG-induced retinal damage is diminished.Animal Model:CPF-induced rat model Dosage:750 mg/kg Administration:i.p.Result:Reduced CPF-induced oxidative stress by increasing the level of GSH and activity of GSH-related enzymes.
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SynonymsGlutamic Acid | Glutamicol | AI3-18472
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PathwayEndocrinology/Hormones
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TargetEstrogen Receptor/ERR
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number56-86-0
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Formula Weight147.13
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Molecular FormulaC5H9NO4
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Purity>98% (HPLC)
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SolubilityIn Vitro:?H2O : 6.25 mg/mL (42.48 mM)
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SMILESC(CC(=O)O)C(C(=O)O)N
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Chemical NameL-glutamic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Giorguieff MF, et al. Presynaptic effect of L-glutamic acid on the release of dopamine in rat striatal slices. Neurosci Lett. 1977 Oct;6(1):73-7.
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